منابع مشابه
Opioids and neuropathic pain.
Opioids are broad spectrum analgesics that may be beneficial to alleviate the intense perception of algesia in patients suffering with pain. They have been one of the most controversial analgesics, in part because of their potential for addiction. Opioids or any currently available analgesic will not provide effective analgesia for every patient with chronic neuropathic pain (NP), but overall o...
متن کاملOpioids and chronic neuropathic pain.
Chronic neuropathic pain is a serious problem resulting from injury to the central or peripheral nervous system; it affects more than 2 million Americans. Despite advances in our understanding of the pathophysiology and molecular biology of neuropathic pain, its clinical management remains disappointing and controversial. Antidepressants and anticonvulsants have been demonstrated to provide ana...
متن کاملOpioids for neuropathic pain.
BACKGROUND The use of opioids for neuropathic pain remains controversial. Studies have been small, have yielded equivocal results, and have not established the long-term risk-benefit ratio of this treatment. OBJECTIVES To assess the efficacy and safety of opioid agonists for the treatment of neuropathic pain. SEARCH STRATEGY We searched the Cochrane Central Register of Controlled Trials (2n...
متن کاملOpioids in chronic pain.
The aim in using opioid drugs in chronic pain is optimal pain relief with a minimum of side effects. A rational approach requires understanding of the clinical pharmacology of opioids given by a variety of routes, for the differences between routes may be greater than the differences between drugs given by the same route. Those using opioids in chronic pain differentiate between their clinical ...
متن کاملPeripheral opioids in inflammatory pain.
Topically applied opioids have provided effective analgesia without adverse effects, including tolerance, in adult patients with painful inflammatory conditions. The presumed mechanism of action is by interaction with opioid receptors which are sited on sensory nerve terminals and which may be up-regulated in inflammation. The use of peripherally acting opioids has not been studied in paediatri...
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ژورنال
عنوان ژورنال: Annals of Oncology
سال: 2008
ISSN: 0923-7534
DOI: 10.1093/annonc/mdm555